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Dr. Julia Nakagawa

Neurosurgeon

  • Research interests and techniques

Translational analysis of structural connectivity of the epileptogenic lesion in focal cortical dysplasia (FCD)

Epilepsy surgery

dMRI and global tractography in vivo

Tissue analysis ex vivo: immunohistochemistry, in situ hybridization, Western Blot

Microscopy

3D reconstruction

 

Donkels D, Huber S, Demerath T, Scheiwe C, Shah MJ, Heers M, Urbach H, Schulze-Bonhage A, Prinz M, Häussler U, Vlachos A, Beck J, Nakagawa JM, Haas CA (2024) Focal cortical dysplasia type II-dependent maladaptive myelination in the human frontal lobe. bioRxiv. doi: 10.1101/2024.03.02.582894 (access to article)

Donkels C, Peters M, Fariña Núñez MT, Nakagawa JM, Kirsch M, Vlachos A, Scheiwe C, Schulze-Bonhage A, Prinz M, Beck J, Haas CA. (2020) Oligodendrocyte lineage and myelination are compromised in the gray matter of focal cortical dysplasia type IIa. Epilepsia 61(1):171-184. doi: 10.1111/epi.16415. (access to article)

Delev D, Oehl B, Steinhoff BJ, Nakagawa J, Scheiwe C, Schulze-Bonhage A, Zentner J. (2019) Surgical Treatment of Extratemporal Epilepsy: Results and Prognostic Factors. Neurosurgery 84(1):242-252. doi: 10.1093/neuros/nyy099. (access to article)

Nakagawa JM, Trippel M, Doostkam S, Mader I, Coenen VA, Reinacher PC. (2018) The stereotactic suboccipitaltranscerebellar approach to lesions of the brainstem and the cerebellum. Clin Neurol Neurosurg. 166:10-15. doi: 10.1016/j.clineuro.2018.01.015. (access to article)

Urbach H, Egger K, Rutkowski K, Nakagawa JM, Schmeiser B, Reisert M, Brandt A, Steinhoff BJ, Schulze-Bonhage A, Hammen T. (2017) Bilateral cingulum fiber reductions in temporal lobe epilepsy with unilateral hippocampal sclerosis. Eur J Radiol. 94:53-57. doi: 10.1016/j.ejrad.2017.07.015. (access to article)

Nakagawa JM, Donkels C, Fauser S, Schulze-Bonhage A, Prinz M, Zentner J, Haas CA. (2017) Characterization of focal cortical dysplasia with balloon cells by layer-specific markers: Evidence for differential vulnerability of interneurons. Epilepsia 58(4):635-645. doi: 10.1111/epi.13690. (access to article)

Donkels C, Pfeifer D, Janz P, Huber S, Nakagawa J, Prinz M, Schulze-Bonhage A, Weyerbrock A, Zentner J, Haas CA. (2017) Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex. Cereb Cortex. 27(2):1558-1572. doi: 10.1093/cercor/bhv346. (access to article)

Fauser S, Häussler U, Donkels C, Huber S, Nakagawa J, Prinz M, Schulze-Bonhage A, Zentner J, Haas CA. (2013) Disorganization of neocortical lamination in focal cortical dysplasia is brain-region dependent: evidence from layer-specific marker expression. Acta Neuropathol Commun. 1:47. doi: 10.1186/2051-5960-1-47. (access to article)