Publikationen
- Evidence gap on antihyperglycemic pharmacotherapy in frail older adults : a systematic review
Bollig, Claudia ; Torbahn, Gabriel ; Bauer, Jürgen M. ; Brefka, Simone ; Dallmeier, Dhayana et al.
- Integriertes Versorgungsmanagement für chronisch erkrankte ältere Menschen in der eigenen Häuslichkeit: Evidenz aus Cochrane-Reviews
Goehner, Anne ; Bitzer, Eva-Maria ; Dreher, Elena ; Farin-Glattacker, Erik ; Heimbach, Bernhard et al.
- Patient-centeredness in older adults with multimorbidity: Results of an online expert Delphi study
Kivelitz, Laura ; Schäfer, Jonas ; Kanat, Manuela ; Mohr, Jil ; Glattacker, Manuela et al.
- Patient-centeredness in the multimorbid elderly: a focus group study
Kanat, Manuela ; Schäfer, Jonas ; Kivelitz, Laura ; Dirmaier, Jörg ; Voigt-Radloff, Sebastian et al.
- Addressing COVID-19 challenges in a randomised controlled trial on exercise interventions in a high-risk population
Kienle, Gunver Sophia ; Werthmann, Paul G. ; Grotejohann, Birgit ; Hundhammer, Tanja ; Schmoor, Claudia et al.
- DAT SPECT predicts survival in patients assessed for differential diagnosis of dementia
Frings, Lars ; Henninger, Franziska ; Treppner, Martin ; Köber, Göran ; Boeker, Martin et al
- Interaction between cognitive reserve and age moderates effect of lesion load on stroke outcome
Umarova, Roza M. ; Schumacher, Lena Valerie ; Schmidt, Charlotte Sophie ; Martin, Markus ; Egger, Karl et al.
- Presurgical screening improves risk prediction for delirium in elective surgery of older patients: The PAWEL RISK study
Eschweiler, Gerhard W. ; Czornik, Manuel ; Herrmann, Matthias L. ; Knauer, Yvonne P. ; Forkavets, Oksana et al.
- Efficacy and safety of pharmacotherapy for Alzheimer’s disease and for behavioural and psychological symptoms of dementia in older patients with moderate and severe functional impairments: a systematic review of controlled trials
Seibert, Moritz ; Mühlbauer, Viktoria ; Holbrook, Jill ; Voigt-Radloff, Sebastian ; Brefka, Simone et al.
- Blazhenets, Ganna; Ma, Yilong; Sörensen, Arnd; et al.: Predictive value of 18F-florbetapir and 18F-FDG PET for conversion from mild cognitive impairment to Alzheimer dementia. In: Journal of nuclear medicine, 2020, 61, 4, 597-603. https://doi.org/10.2967/jnumed.119.230797
- Bollig, Claudia; Torbahn, Gabriel; Bauer, Jürgen M.; et al.: Evidence gap on antihyperglycemic pharmacotherapy in frail older adults : a systematic review. In: Zeitschrift für Gerontologie und Geriatrie, 2020 https://doi.org/10.1007/s00391-020-01724-3
- Frings, Lars; Heimbach, Bernhard; Meyer, Philipp T.; Hellwig, Sabine; et al; Intrinsic alertness is impaired in patients with nigrostriatal degeneration: a prospective study with reference to [123I]FP-CIT SPECT and [18F]FDG PET; In: Journal of Alzheimer's disease; 10.3233/jad-191277; https://freidok.uni-freiburg.de/data/174862
- Glattacker, Manuela; Kanat, Manuela; Schäfer, Jonas; et al.: Availability and quality of assessment instruments on patient-centredness in the multimorbid elderly (AQuA-PCE): a study protocol of a systematic review. In: BMJ open, 2020, 10, 2, e033273. https://doi.org/10.1136/bmjopen-2019-033273
- Goehner, Anne; Bitzer, Eva-Maria; Dreher, Elena; et al.: Integriertes Versorgungsmanagement für chronisch erkrankte ältere Menschen in der eigenen Häuslichkeit: Evidenz aus Cochrane-Reviews. In: Zeitschrift für Gerontologie und Geriatrie, 2020 https://doi.org/10.1007/s00391-020-01796-1
- Kienle, Gunver Sophia; Werthmann, Paul G.; Grotejohann, Birgit; et al.: A multi-centre, parallel-group, randomised controlled trial to assess the efficacy and safety of eurythmy therapy and tai chi in comparison with standard care in chronically ill elderly patients with increased risk of falling (ENTAiER): a trial protocol. In: BMC geriatrics, 2020, 20, 1, 108. https://doi.org/10.1186/s12877-020-1503-6
- Krebs, Christine; Klöppel, Stefan; Heimbach, Bernhard; et al.: Education moderates the effect of tDCS on episodic memory performance in cognitively impaired patients. In: Brain stimulation, 2020, 13, 5, 1396-1398. https://doi.org/10.1016/j.brs.2020.07.008
- Rhein, Cosima; Mühle, Christiane; Lenz, Bernd; et al.: Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly. In: Brain research bulletin, 2020, 161, 13-20. https://doi.org/10.1016/j.brainresbull.2020.05.001
- Schröter, Nils; Blazhenets, Ganna; Frings, Lars; et al.: Tau imaging in the 4-repeat-tauopathies progressive supranuclear palsy and corticobasal syndrome : a 11C-pyridinyl-butadienyl-benzothiazole 3 PET Pilot Study. In: Clinical nuclear medicine, 2020, 45, 4, 283-287. https://doi.org/10.1097/rlu.0000000000002949
- Voigt-Radloff, Sebastian; Bollig, Claudia; Torbahn, Gabriel; et al.: Maßnahmen zur Optimierung von Medikamentenverordnungen für ältere Menschen in Pflegeeinrichtungen. In: Zeitschrift für Gerontologie und Geriatrie, 2020, 53, 1, 37-43. https://doi.org/10.1007/s00391-019-01673-6
- Bauer, Jürgen M.; Denkinger, Michael; Voigt-Radloff, Sebastian; et al.: Aktuelle Cochrane-Reviews, kommentiert aus geriatrischer Perspektive : Orientierung in Zeiten der Informationsoverkills. In: Zeitschrift für Gerontologie und Geriatrie, 2019, 52, 2, 111-112. https://doi.org/10.1007/s00391-019-01515-5
- ennett, Sally; Laver, Kate; Voigt-Radloff, Sebastian; et al.: Occupational therapy for people with dementia and their family carers provided at home: a systematic review and meta-analysis. In: BMJ open, 2019, 9, 11, e026308. https://doi.org/10.1136/bmjopen-2018-026308
- Blazhenets, Ganna; Ma, Yilong; Sörensen, Arnd; et al.: Principal components analysis of brain metabolism predicts development of Alzheimer dementia. In: Journal of nuclear medicine, 2019, 60, 6, 837-843. https://doi.org/10.2967/jnumed.118.219097
- Brefka, Simone; Dallmeier, Dhayana; Mühlbauer, Viktoria; et al.: A proposal for the retrospective identification and categorization of older people with functional impairments in scientific studies - recommendations of the medication and quality of life in frail older persons (MedQoL) research group. In: Journal of the American Medical Directors Association, 2019, 20, 2, 138-146. https://doi.org/10.1016/j.jamda.2018.11.008
- Brich, Jochen; Baten, Verena; Wußmann, Judith; et al.: Detecting delirium in elderly medical emergency patients: validation and subsequent modification of the German Nursing Delirium Screening Scale. In: Internal and emergency medicine, 2019, 14, 5, 767-776. https://doi.org/10.1007/s11739-018-1989-5
- Brumberg, Joachim; Blazhenets, Ganna; Schröter, Nils; et al.: Imaging cardiac sympathetic innervation with MIBG: linear conversion of the heart-to-mediastinum ratio between different collimators. In: EJNMMI physics, 2019, 6, 1, 12. https://doi.org/10.1186/s40658-019-0250-2
- Brühmann, Boris A.; Reese, Christina; Kaier, Klaus; et al.: A complex health services intervention to improve medical care in long-term care homes: study protocol of the controlled coordinated medical care (CoCare) study. In: BMC health services research, 2019, 19, 332. https://doi.org/10.1186/s12913-019-4156-4
- Frank, Fabian; Bjerregaard, Frederike; Bengel, Jürgen; et al.: Local, collaborative, stepped and personalised care management for older people with chronic diseases (LoChro): study protocol of a randomised comparative effectiveness trial. In: BMC geriatrics, 2019, 19, 1, 64. https://doi.org/10.1186/s12877-019-1088-0
- Goehner, Anne; Kricheldorff, Cornelia; Bitzer, Eva-Maria: Trained volunteers to support chronically ill, multimorbid elderly between hospital and domesticity - a systematic review of one-on-one-intervention types, effects, and underlying training concepts. In: BMC geriatrics, 2019, 19, 126. https://doi.org/10.1186/s12877-019-1130-2
- Grochtdreis, Thomas; Brettschneider, Christian; Bjerregaard, Frederike; et al.: Cost-effectiveness analysis of collaborative treatment of late-life depression in primary care (GermanIMPACT). In: European psychiatry, 2019, 57, 10-18. https://doi.org/10.1016/j.eurpsy.2018.12.007
- Hellwig, Sabine; Frings, Lars; Bormann, Tobias; et al.: Amyloid imaging for differential diagnosis of dementia: incremental value compared to clinical diagnosis and [18F]FDG PET. In: European journal of nuclear medicine and molecular imaging, 2019, 46, 2, 312-323. https://doi.org/10.1007/s00259-018-4111-3
- Heupel‐Reuter, Miriam; Denkinger, Michael; Bauer, Jürgen M.; et al.: Blutdrucksenkende Behandlung zur Prävention von Schlaganfallrezidiven, schwerwiegenden vaskulären Ereignissen und Demenz bei Patienten mit Schlaganfall oder transitorischer ischämischer Attacke in der Vorgeschichte. In: Zeitschrift für Gerontologie und Geriatrie, 2019, 52, 2, 195-197. https://doi.org/10.1007/s00391-019-01521-7
- Heupel‐Reuter, Miriam; Klöppel, Stefan; Bauer, Jürgen M.; et al.: Medikamentöse Interventionen gegen Apathie bei Alzheimer. In: Zeitschrift für Gerontologie und Geriatrie, 2019, 52, 5, 457-459. https://doi.org/10.1007/s00391-019-01580-w
- Heupel‐Reuter, Miriam; Maurer, Christoph; Becker, Clemens; et al.: Übungen und multimodale Interventionen zur Vorbeugung von Stürzen bei selbstständig lebenden älteren Menschen. In: Zeitschrift für Gerontologie und Geriatrie, 2019, 52, 7, 694-700. https://doi.org/10.1007/s00391-019-01604-5
- Heupel‐Reuter, Miriam; Zieschang, Tania; Hoffmann, Falk; et al.: Interventionen zur Verbesserung der Palliativversorgung älterer Menschen, die in Pflegeeinrichtungen leben. In: Zeitschrift für Gerontologie und Geriatrie, 2019, 52, 8, 758-760. https://doi.org/10.1007/s00391-019-01615-2
- Jain, Gaurav; Stuendl, Anne; Rao, Pooja; et al.: A combined miRNA–piRNA signature to detect Alzheimer’s disease. In: Translational psychiatry, 2019, 9, 1, 250. https://doi.org/10.1038/s41398-019-0579-2
- Minkova, Lora; Peter, Jessica; Abdulkadir, Ahmed; et al.: Determinants of inter-individual variability in corticomotor excitability induced by paired associative stimulation. In: Frontiers in neuroscience, 2019, 13, 841. https://doi.org/10.3389/fnins.2019.00841
- Mühlbauer, Viktoria; Dallmeier, Dhayana; Brefka, Simone; et al.: The pharmacological treatment of arterial hypertension in frail, older patients. In: Deutsches Aerzteblatt International, 2019, 116, 3, 23-30. https://doi.org/10.3238/arztebl.2019.0023
- Schiller, Florian; Frings, Lars; Thurow, Johannes; et al.: Limits for reduction of acquisition time and administered activity in 18F-FDG PET studies of alzheimer dementia and frontotemporal dementia. In: Journal of nuclear medicine, 2019, 60, 12, 1764-1770. https://doi.org/10.2967/jnumed.119.227132
- Schoeb, Dominik S.; Wullich, Bernd; Dürschmied, D.; et al.: Therapie des benignen Prostatasyndroms beim geriatrischen Patienten – Anwendung und Limitation medizinischer Leitlinien. In: Der Urologe, 2019, 58, 9, 1029-1038. https://doi.org/10.1007/s00120-019-0988-0
- Sánchez, Alba; Thomas, Christine; Deeken, Friederike; et al.: Patient safety, cost-effectiveness, and quality of life: reduction of delirium risk and postoperative cognitive dysfunction after elective procedures in older adults - study protocol for a stepped-wedge cluster randomized trial (PAWEL Study). In: Trials, 2019, 20, 71. https://doi.org/10.1186/s13063-018-3148-8
- Sörensen, Arnd; Blazhenets, Ganna; Rücker, Gerta; et al.: Prognosis of conversion of mild cognitive impairment to Alzheimer's dementia by voxel-wise Cox regression based on FDG PET data. In: NeuroImage: Clinical, 2019, 21, 101637. https://doi.org/10.1016/j.nicl.2018.101637
- Baumgartner A, Frings L, Schiller F, Stich O, Mix M, Egger K, Schluh G, Rauer S, Meyer PT:
Regional neuronal activity in patients with relapsing remitting multiple sclerosis.
Acta Neurol Scand, 2018; 138 (6): 466-474.
- Bormann T, Frings L, Dressing A, Glauche V, Weiller C:
Do all visual deficits cause pure alexia? Dissociations between visual processing and reading suggest "no".
Brain Cognition, 2018; 125:69-77.
- Frings L, Hellwig S, Bormann T, Spehl TS, Buchert R, Meyer PT:
Amyloid load but not regional glucose metabolism predicts conversion to Alzheimer's dementia in a memory clinic population.
Eur J Nucl Med Mol I, 2018; 45 (8): 1442-1448.
- Gohner A, Hull M, Voigt-Radloff S:
[Non-pharmacological treatment of dementia in geriatric psychiatry care units : Scoping review].
Z Gerontol Geriatr, 2018; 51 (2): 169-183.
- Hellwig S, Frings L, Bormann T, Vach W, Buchert R, Meyer PT:
Amyloid imaging for differential diagnosis of dementia: incremental value compared to clinical diagnosis and [(18)F]FDG PET.
Eur J Nucl Med Mol I, 2018; 259: 1-12.
- Hellwig S, Frings L, Masuch A, Vach W, Domschke K, Normann C, Meyer PT:
Antidepressant treatment effects on dopamine transporter availability in patients with major depression: a prospective (123)I-FP-CIT SPECT imaging genetic study.
J Neural Transm, 2018; 125 (6):995-1005.
- · Kammermeier S, Maierbeck K, Dietrich L, Plate A, Lorenzl S, Singh A, Botzel K, Maurer C:
Qualitative postural control differences in Idiopathic Parkinson's Disease vs. ProgressiveSupranuclear Palsy with dynamic-on-static platform tilt.
Clin Neurophysiol, 2018; 129 (6):1137-1147.
- Kloppel S, Kotschi M, Peter J, Egger K, Hausner L, Frolich L, Forster A, Heimbach B, Normann
C, Vach W, Urbach H, Abdulkadir A:
Separating Symptomatic Alzheimer's Disease from Depression based on Structural MRI.
J Alzheimers Dis, 2018; 63 (1): 353-363.2 / 2
- Kloppel S, Yang S, Kellner E, Reisert M, Heimbach B, Urbach H, Linn J, Weidauer S, Andres
T, Brose M, Lahr J, Lutzen N, Meyer PT, Peter J, Abdulkadir A, Hellwig S, Egger K:
Voxel-wisedeviations from healthy aging for the detection of region-specific atrophy.
Neuroimage-clin, 2018;20: 851-860.
- van Kordelaar J, Pasma JH, Cenciarini M, Schouten AC, van der Kooij H, Maurer C:
TheReliance on Vestibular Information During Standing Balance Control Decreases With Severity of Vestibular Dysfunction.
Front Neurol, 2018; 9: 371-371.
- Rauschendorf MA, Jost M, Stock F, Zimmer A, Rösler B, Rijntjes M, Piroth T, Coenen VA, Reinacher PC, Meyer PT, Frings L, Weiller C, Fischer J, Klebe S.
- Novel compound heterozygous synaptojanin-1 mutation causes l-dopa-responsive dystonia-parkinsonism syndrome.Mov Disord. 2017 Mar;32(3):478-480. doi: 10.1002/mds.26876. Epub 2016 Nov 21. No abstract available. PMID:27869329
- Voigt-Radloff S, de Werd MM, Leonhart R, Boelen DH, Olde Rikkert MG, Fliessbach K, Klöppel S, Heimbach B, Fellgiebel A, Dodel R, Eschweiler GW, Hausner L, Kessels RP, Hüll M
Structured relearning of activities of daily living in dementia: the randomized controlled REDALI-DEM trial on errorless learning.Alzheimers Res Ther. 2017 Mar 23;9(1):22. doi: 10.1186/s13195-017-0247-9.PMID:28335810
- Araque Caballero MÁ, Klöppel S, Dichgans M, Ewers M; Alzheimer’s Disease Neuroimaging Initiative. Spatial Patterns of Longitudinal Gray Matter Change as Predictors of Concurrent Cognitive Decline in Amyloid Positive Healthy Subjects.. J Alzheimers Dis. 2016 Nov 1;55(1):343-358. PMID: 27662291
- Tebartz van Elst L, Maier S, Klöppel S, Graf E, Killius C, Rump M, Sobanski E, Ebert D, Berger M, Warnke A, Matthies S, Perlov E, Philipsen A. The effect of methylphenidate intake on brain structure in adults with ADHD in a placebo-controlled randomized trial. J Psychiatry Neurosci. 2016 Oct;41(6):422-430. PMID: 27575717
- Peter J, Kaiser J, Landerer V, Köstering L, Kaller CP, Heimbach B, Hüll M, Bormann T, Klöppel S. Category and design fluency in mild cognitive impairment: Performance, strategy use, and neural correlates. Neuropsychologia. 2016 Sep 30;93(Pt A):21-29. doi: 10.1016/j.neuropsychologia.2016.09.024. PMID: 27693701
- Leyhe T, Reynolds CF 3rd, Melcher T, Linnemann C, Klöppel S, Blennow K, Zetterberg H, Dubois B, Lista S, Hampel H. A common challenge in older adults: Classification, overlap, and therapy of depression and dementia. Alzheimers Dement. 2016 Sep 28. pii: S1552-5260(16)32887-4. doi: 10.1016/j.jalz.2016.08.007. Review. PMID: 27693188
- Beume LA, Martin M, Kaller CP, Klöppel S, Schmidt CS, Urbach H, Egger K, Rijntjes M, Weiller C, Umarova RM. Visual neglect after left-hemispheric lesions: a voxel-based lesion-symptom mapping study in 121 acute stroke patients. Exp Brain Res. 2016 Sep 16. PMID: 27637595
- Frase L, Piosczyk H, Zittel S, Jahn F, Selhausen P, Krone L, Feige B, Mainberger F, Maier JG, Kuhn M, Klöppel S, Normann C, Sterr A, Spiegelhalder K, Riemann D, Nitsche MA, Nissen C. Modulation of Total Sleep Time by Transcranial Direct Current Stimulation (tDCS).Neuropsychopharmacology. 2016 Sep;41(10):2577-86. doi: 10.1038/npp.2016.65. PMID: 27143601
- Habich A, Canals S, Klöppel S. Tuning noninvasive brain stimulation with MRI to cope with intersubject variability. Curr Opin Neurol. 2016 Aug;29(4):453-8. doi: 10.1097/WCO.0000000000000353. PMID: 27257946
- Vemuri P, Fields J, Peter J, Klöppel S. Cognitive interventions in Alzheimer's and Parkinson's diseases: emerging mechanisms and role of imaging. Curr Opin Neurol. 2016 Aug;29(4):405-11. doi: 10.1097/WCO.0000000000000346. PMID: 27213773
- Kuhn M, Wolf E, Maier JG, Mainberger F, Feige B, Schmid H, Bürklin J, Maywald S, Mall V, Jung NH, Reis J, Spiegelhalder K, Klöppel S, Sterr A, Eckert A, Riemann D, Normann C, Nissen C. Sleep recalibrates homeostatic and associative synaptic plasticity in the human cortex. Nat Commun. 2016 Aug 23;7:12455. doi: 10.1038/ncomms12455. PMID: 27551934
- Orth M, Gregory S, Scahill RI, Mayer IS, Minkova L, Klöppel S, Seunarine KK, Boyd L, Borowsky B, Reilmann R, Bernhard Landwehrmeyer G, Leavitt BR, Roos RA, Durr A, Rees G, Rothwell JC, Langbehn D, Tabrizi SJ; TRACK-On Investigators.. Natural variation in sensory-motor white matter organization influences manifestations of Huntington's disease. Hum Brain Mapp. 2016 Aug 1. doi: 10.1002/hbm.23332. PMID: 27477323
- Hellwig S, Brioschi S, Dieni S, Frings L, Masuch A, Blank T, Biber K. Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice. Brain Behav Immun. 2016 Jul;55:126-37. doi: 10.1016/j.bbi.2015.11.008. PubMed PMID: 26576722
- Frings L, Spehl TS, Hüll M, Meyer PT. Left Anterior Temporal Glucose Metabolism and not Amyloid-beta Load Predicts Naming Impairment in Alzheimer's Disease. Curr Alzheimer Res. 2016;13(6):678-81. PubMed PMID: 27001678
- Underhill HR, Kitzman JO, Hellwig S, Welker NC, Daza R, Baker DN, Gligorich KM, Rostomily RC, Bronner MP, Shendure J. Fragment Length of Circulating Tumor DNA. PLoS Genet. 2016 Jul 18;12(7):e1006162. doi: 10.1371/journal.pgen.1006162. PMID: 27428049
- Peter J, Lahr J, Minkova L, Lauer E, Grothe MJ, Teipel S, Köstering L, Kaller CP, Heimbach B, Hüll M, Normann C, Nissen C, Reis J, Klöppel S. Contribution of the Cholinergic System to Verbal Memory Performance in Mild Cognitive Impairment. J Alzheimers Dis. 2016 Jun 18;53(3):991-1001. doi: 10.3233/JAD-160273. PMID: 27340852
- de Werd MM, Hoelzenbein AC, Boelen DH, Rikkert MG, Hüell M, Kessels RP,Voigt-Radloff S. Interrater Reliability and Concurrent Validity of a New RatingScale to Assess the Performance of Everyday Life Tasks in Dementia: The CoreElements Method. Am J Alzheimers Dis Other Demen. 2016 Jun 14. PubMed PMID: 27303065
- Lahr J, Paßmann S, List J, Vach W, Flöel A, Klöppel S. Effects of Different Analysis Strategies on Paired Associative Stimulation. A Pooled Data Analysis from Three Research Labs. PLoS One. 2016 May 4;11(5):e0154880. doi: 10.1371/journal.pone.0154880. PMID: 27144307
- Voigt-Radloff S, Blümle A, Meerpohl J. Kommentar zur TIDier Checkliste.Gesundheitswesen. 2016 Mar;78(3):189-90. PubMed PMID: 2682440
- Brueggen K, Grothe MJ, Dyrba M, Fellgiebel A, Fischer F, Filippi M, Agosta F, Nestor P, Meisenzahl E, Blautzik J, Frölich L, Hausner L, Bokde AL, Frisoni G, Pievani M, Klöppel S, Prvulovic D, Barkhof F, Pouwels PJ, Schröder J, Hampel H, Hauenstein K, Teipel S. The European DTI Study on Dementia - A multicenter DTI and MRI study on Alzheimer's disease and Mild Cognitive Impairment. Neuroimage. 2016 Apr 2. pii: S1053-8119(16)30011-8. doi: 10.1016/j.neuroimage.2016.03.067. PMID: 27046114
- Umarova RM, Nitschke K, Kaller CP, Klöppel S, Beume L, Mader I, Martin M, Hennig J, Weiller C. Predictors and signatures of recovery from neglect in acute stroke.Ann Neurol. 2016 Apr;79(4):673-86. doi: 10.1002/ana.24614. PMID: 26873402
- Lahr J, Peter J, Minkova L, Lauer E, Reis J, Heimbach B, Hüll M, Normann C, Nissen C, Klöppel S.
No difference in paired associative stimulation induced cortical neuroplasticity between patients with mild cognitive impairment and elderly controls. Clin Neurophysiol. 2016 Feb;127(2):1254-60. doi: 10.1016/j.clinph.2015.08.010. PMID: 26394910 - Krone L, Frase L, Piosczyk H, Selhausen P, Zittel S, Jahn F, Kuhn M, Feige B, Mainberger F, Klöppel S, Riemann D, Spiegelhalder K, Baglioni C, Sterr A, Nissen C. Top-down control of arousal and sleep: Fundamentals and clinical implications. Sleep Med Rev. 2016 Jan 14. pii: S1087-0792(16)00002-2. doi: 10.1016/j.smrv.2015.12.005. Review. PMID: 26883160
- Kuhn M, Mainberger F, Feige B, Maier JG, Mall V, Jung NH, Reis J, Klöppel S, Normann C, Nissen C. State-Dependent Partial Occlusion of Cortical LTP-Like Plasticity in Major Depression. Neuropsychopharmacology. 2015 Oct 7. doi: 10.1038/npp.2015.310
- Klöppel S, Lauer E, Peter J, Minkova L, Nissen C, Normann C, Reis J, Mainberger F, Bach M, Lahr J. LTP-like plasticity in the visual system and in the motor system appear related in young and healthy subjects. Front Hum Neurosci. 2015 Sep 24;9:506. doi: 10.3389/fnhum.2015.00506. eCollection 2015
- Lahr J, Peter J, Minkova L, Lauer E, Reis J, Heimbach B, Hüll M, Normann C, Nissen C, Klöppel S. No difference in paired associative stimulation induced cortical neuroplasticity between patients with mild cognitive impairment and elderly controls. Clin Neurophysiol. 2015 Aug 31. pii: S1388-2457(15)00761-0. doi: 10.1016/j.clinph.2015.08.010
- Brueggen K, Dyrba M, Barkhof F, Hausner L, Filippi M, Nestor PJ, Hauenstein K, Klöppel S, Grothe MJ, Kasper E, Teipel SJ. Basal Forebrain and Hippocampus as Predictors of Conversion to Alzheimer's Disease in Patients with Mild Cognitive Impairment - A Multicenter DTI and Volumetry Study. J Alzheimers Dis. 2015 Aug 28;48(1):197-204. doi: 10.3233/JAD-150063.
- Klöppel S, Peter J, Ludl A, Pilatus A, Maier S, Mader I, Heimbach B, Frings L, Egger K, Dukart J, Schroeter ML, Perneczky R, Häussermann P, Vach W, Urbach H, Teipel S, Hüll M, Abdulkadir A. Applying Automated MR-Based Diagnostic Methods to the Memory Clinic: A Prospective Study. J Alzheimers Dis. 2015 Aug 11;47(4):939-54. doi: 10.3233/JAD-150334.
- Lahr J, Schwartz C, Heimbach B, Aertsen A, Rickert J, Ball T. Invasive brain-machine interfaces: a survey of paralyzed patients`attitudes, knowledge and methods of information retrieval. J Neural Eng. 2015; 12 (043001): 8pp
- Ossenkoppele R, Jansen WJ, Rabinovici GD, Knol DL, van der Flier WM, van Berckel BN, Scheltens P, Visser PJ; Amyloid PET Study Group, Verfaillie SC, Zwan MD, Ad-riaanse SM, Lammertsma AA, Barkhof F, Jagust WJ, Miller BL, Rosen HJ, Landau SM, Villemagne VL, Rowe CC, Lee DY, Na DL, Seo SW, Sarazin M, Roe CM, Sabri O, Bar-thel H, Koglin N, Hodges J, Leyton CE, Vandenberghe R, van Laere K, Drzezga A, Fors-ter S, Grimmer T, Sánchez-Juan P, Carril JM, Mok V, Camus V, Klunk WE, Cohen AD, Meyer PT, Hellwig S, Newberg A, Frederiksen KS, Fleisher AS, Mintun MA, Wolk DA, Nordberg A, Rinne JO, Chételat G, Lleo A, Blesa R, Fortea J, Madsen K, Rodrigue KM, Brooks DJ. Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis. JAMA. 2015 May 19;313(19):1939-49.
- Jansen WJ, Ossenkoppele R, Knol DL, Tijms BM, Scheltens P, Verhey FR, Visser PJ; Amyloid Biomarker Study Group, Aalten P, Aarsland D, Alcolea D, Alexander M, Almdahl IS, Arnold SE, Baldeiras I, Barthel H, van Berckel BN, Bibeau K, Blennow K, Brooks DJ, van Buchem MA, Camus V, Cavedo E, Chen K, Chetelat G, Cohen AD, Drzezga A, En-gelborghs S, Fagan AM, Fladby T, Fleisher AS, van der Flier WM, Ford L, Förster S, Fortea J, Foskett N, Frederiksen KS, Freund-Levi Y, Frisoni GB, Froelich L, Gabrye-lewicz T, Gill KD, Gkatzima O, Gómez-Tortosa E, Gordon MF, Grimmer T, Hampel H, Hausner L, Hellwig S, Herukka SK, Hildebrandt H, Ishihara L, Ivanoiu A, Jagust WJ, Jo-hannsen P, Kandimalla R, Kapaki E, Klimkowicz-Mrowiec A, Klunk WE, Köhler S, Koglin N, Kornhuber J, Kramberger MG, Van Laere K, Landau SM, Lee DY, de Leon M, Lisetti V, Lleó A, Madsen K, Maier W, Marcusson J, Mattsson N, de Mendonça A, Meulenbroek O, Meyer PT, Mintun MA, Mok V, Molinuevo JL, Møllergård HM, Morris JC, Mroczko B, Van der Mussele S, Na DL, Newberg A, Nordberg A, Nordlund A, Novak GP, Par-askevas GP, Parnetti L, Perera G, Peters O, Popp J, Prabhakar S, Rabinovici GD, Ra-makers IH, Rami L, Resende de Oliveira C, Rinne JO, Rodrigue KM, Rodríguez-Rodríguez E, Roe CM, Rot U, Rowe CC, Rüther E, Sabri O, Sanchez-Juan P, Santana I, Sarazin M, Schröder J, Schütte C, Seo SW, Soetewey F, Soininen H, Spiru L, Struyfs H, Teunissen CE, Tsolaki M, Vandenberghe R, Verbeek MM, Villemagne VL, Vos SJ, van Waalwijk van Doorn LJ, Waldemar G, Wallin A, Wallin ÅK, Wiltfang J, Wolk DA, Zboch M, Zetterberg H. Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. JAMA. 2015 May 19;313(19):1924-38.
- Spehl TS, Hellwig S, Amtage F, Weiller C, Bormann T, Weber WA, Hüll M, Meyer PT, Frings L. Syndrome-specific patterns of regional cerebral glucose metabolism in posteri-or cortical atrophy in comparison to dementia with Lewy bodies and Alzheimer's disease--a [F-18]-FDG pet study. J Neuroimaging. 2015 Mar-Apr;25(2):281-8.
- Spehl TS, Frings L, Hellwig S, Weiller C, Hüll M, Meyer PT, Amtage F. Role of semi-quantitative assessment of regional binding potential in 123I-FP-CIT SPECT for the dif-ferentiation of frontotemporal dementia, dementia with Lewy bodies, and Alzheimer's dementia. Clin Nucl Med. 2015 Jan;40(1):e27-33.
- Voigt-Radloff S, Ruf G, Vogel A, van Nes F, Hüll M. Occupational therapy for elderly. Evidence mapping of randomised controlled trials from 2004-2012. Z Gerontol Geriatr. 2015 Jan;48(1):52-72.
- Schmitter D, Roche A, Maréchal B, Ribes D, Abdulkadir A, Bach-Cuadra M, Daducci A, Granziera C, Klöppel S, Maeder P, Meuli R, Krueger G; Alzheimer's Disease Neuroim-aging Initiative. An evaluation of volume-based morphometry for prediction of mild cogni-tive impairment and Alzheimer's disease. Neuroimage Clin. 2014 Nov 8;7:7-17.
- Niethammer M, Tang CC, Feigin A, Allen PJ, Heinen L, Hellwig S, Amtage F, Hanspal E, Vonsattel JP, Poston KL, Meyer PT, Leenders KL, Eidelberg D. A disease-specific met-abolic brain network associated with corticobasal degeneration. Brain. 2014 Nov;137(Pt 11):3036-46.
- Scheller E, Minkova L, Leitner M, Klöppel S. Attempted and successful compensation in preclinical and early manifest neurodegeneration - a review of task FMRI studies. Front Psychiatry. 2014 Sep 29;5:132.
- Amtage F, Maurer C, Hellwig S, Tüscher O, Kreft A, Weiller C, Rijntjes M, Winkler C, Meyer PT. Functional correlates of vertical gaze palsy and other ocular motor deficits in PSP: an FDG-PET study. Parkinsonism Relat Disord. 2014 Aug;20(8):898-906.
- Meyer PT, Hellwig S. Update on SPECT and PET in parkinsonism - part 1: imaging for differential diagnosis. Curr Opin Neurol. 2014 Aug;27(4):390-7.
- Meyer PT, Frings L, Hellwig S. Update on SPECT and PET in parkinsonism - part 2: biomarker imaging of cognitive impairment in Lewy-body diseases. Curr Opin Neurol. 2014 Aug;27(4):398-404.
- Hellwig S, Reinhard M, Amtage F, Guschlbauer B, Buchert R, Tüscher O, Weiller C, Niesen WD, Meyer PT. Transcranial sonography and [18F]fluorodeoxyglucose positron emission tomography for the differential diagnosis of parkinsonism: a head-to-head comparison. Eur J Neurol. 2014 Jun;21(6):860-6.
- Meyer PT, Amtage F, Hellwig S. [Differential diagnostics of Parkinson's disease with nuclear medicine procedures]. Nervenarzt. 2014 Jun;85(6):680-9.
- Amtage F, Hellwig S, Kreft A, Spehl T, Glauche V, Winkler C, Rijntjes M, Hellwig B, Weiller C, Weber WA, Tüscher O, Meyer PT. Neuronal correlates of clinical asymmetry in progressive supranuclear palsy. Clin Nucl Med. 2014 Apr;39(4):319-25.
- Frings L, Yew B, Flanagan E, Lam BY, Hüll M, Huppertz HJ, Hodges JR, Hornberger M. Longitudinal grey and white matter changes in frontotemporal dementia and Alzheimer's disease. PLoS One. 2014 Mar 3;9(3):e90814.
- Peter J, Scheef L, Abdulkadir A, Boecker H, Heneka M, Wagner M, Koppara A, Klöppel S, Jessen F; Alzheimer's Disease Neuroimaging Initiative. Gray matter atrophy pattern in elderly with subjective memory impairment. Alzheimers Dement. 2014 Jan;10(1):99-108.
- Peter J, Abdulkadir A, Kaller C, Kümmerer D, Hüll M, Vach W, Klöppel S. Subgroups of Alzheimer's disease: stability of empirical clusters over time. J Alzheimers Dis. 2014;42(2):651-61.
- Teipel SJ, Grothe MJ, Filippi M, Fellgiebel A, Dyrba M, Frisoni GB, Meindl T, Bokde AL, Hampel H, Klöppel S, Hauenstein K; EDSD study group. Fractional anisotropy changes in Alzheimer's disease depend on the underlying fiber tract architecture: a multiparamet-ric DTI study using joint independent component analysis. J Alzheimers Dis. 2014;41(1):69-83.
- Kilimann I, Grothe M, Heinsen H, Alho EJ, Grinberg L, Amaro E Jr, Dos Santos GA, da Silva RE, Mitchell AJ, Frisoni GB, Bokde AL, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Teipel SJ. Subregional basal forebrain atrophy in Alzheimer's disease: a multicenter study. J Alzheimers Dis. 2014;40(3):687-700.3
- Voigt-Radloff S, Lang B, Antes G. [Potentials for research and innovations in allied health professions in Germany]. Z Evid Fortbild Qual Gesundhwes. 2014;108 Suppl 1:S4-8.
- Lohkamp M, Braun C, Wasner M, Voigt-Radloff S. [Potential analysis for research on physiotherapy-led treadmill training in Parkinson's disease]. Z Evid Fortbild Qual Ge-sundhwes. 2014;108 Suppl 1:S29-35.
- Müller C, Glässel A, Marotzki U, Voigt-Radloff S. [Potential analyses for research on occupational therapy-led training of activities of daily living in stroke patients]. Z Evid Fortbild Qual Gesundhwes. 2014;108 Suppl 1:S36-44.
- Kempf S, Lauer N, Corsten S, Voigt-Radloff S. [Potential analysis of research on speech therapy-led communication training in aphasia following stroke]. Z Evid Fortbild Qual Gesundhwes. 2014;108 Suppl 1:S45-52.
- Vives-Gilabert Y, Abdulkadir A, Kaller CP, Mader W, Wolf RC, Schelter B, Klöppel S. Detection of preclinical neural dysfunction from functional connectivity graphs derived from task fMRI. An example from degeneration. Psychiatry Res. 2013 Dec 30;214(3):322-30.
- Hellwig S, Kreft A, Amtage F, Tüscher O, Winz OH, Hellwig B, Weiller C, Weber WA, Vach W, Meyer PT. 123I-iodobenzamide SPECT is not an independent predictor of do-paminergic responsiveness in patients with suspected atypical parkinsonian syndromes. J Nucl Med. 2013 Dec;54(12):2081-6.
- Frings L, Dressel K, Abel S, Mader I, Glauche V, Weiller C, Hüll M. Longitudinal cerebral diffusion changes reflect progressive decline of language and cognition. Psychiatry Res. 2013 Dec 30;214(3):395-401.
- Hellwig S, Frings L, Bormann T, Kreft A, Amtage F, Spehl TS, Weiller C, Tüscher O, Meyer PT. Neural correlates of cognitive dysfunction in Lewy body diseases and tauopa-thies: combined assessment with FDG-PET and the CERAD test battery. Brain Lang. 2013 Nov;127(2):307-14.
- Frings L, Spehl TS, Weber WA, Hüll M, Meyer PT. Amyloid-β load predicts medial temporal lobe dysfunction in Alzheimer dementia. J Nucl Med. 2013 Nov;54(11):1909-14.
- Hellwig S, Gutmann V, Trimble MR, van Elst LT. Cerebellar volume is linked to cognitive function in temporal lobe epilepsy: a quantitative MRI study. Epilepsy Behav. 2013 Aug;28(2):156-62.
- Abdulkadir A, Ronneberger O, Wolf RC, Pfleiderer B, Saft C, Klöppel S. Functional and structural MRI biomarkers to detect pre-clinical neurodegeneration. Curr Alzheimer Res. 2013 Feb;10(2):125-34.
- Amtage F, Spehl TS, Hellwig S, Sahm U, Hellwig B, Reuland P, Weiller C, Weber WA, Winkler C, Meyer PT. Assessment of striatal dopamine D2/D3 receptor availability with PET and 18F-desmethoxyfallypride: comparison of imaging protocols suited for clinical routine. J Nucl Med. 2012 Oct;53(10):1558-64.
- Hellwig S, Amtage F, Kreft A, Buchert R, Winz OH, Vach W, Spehl TS, Rijntjes M, Hell-wig B, Weiller C, Winkler C, Weber WA, Tüscher O, Meyer PT. [¹⁸F]FDG-PET is superior to [¹²³I]IBZM-SPECT for the differential diagnosis of parkinsonism. Neurology. 2012 Sep 25;79(13):1314-22.
- Winz OH, Hellwig S, Mix M, Weber WA, Mottaghy FM, Schäfer WM, Meyer PT. Image quality and data quantification in dopamine transporter SPECT: advantage of 3-dimensional OSEM reconstruction? Clin Nucl Med. 2012 Sep;37(9):866-71.
- Frings L, Mader I, Landwehrmeyer BG, Weiller C, Hüll M, Huppertz HJ. Quantifying change in individual subjects affected by frontotemporal lobar degeneration using auto-mated longitudinal MRI volumetry. Hum Brain Mapp. 2012 Jul;33(7):1526-35.
- Klöppel S, Abdulkadir A, Jack CR Jr, Koutsouleris N, Mourão-Miranda J, Vemuri P. Diagnostic neuroimaging across diseases. Neuroimage. 2012 Jun;61(2):457-63.
- Ewers M, Grewe T, Höppner H, Huber W, Sayn-Wittgenstein F, Stemmer R, Voigt-Radloff S, Walkenhorst U. [Research in the health care professions]. Dtsch Med Woch-enschr. 2012 Jun;137 Suppl 2:S34-6.
- Hellwig S, Mamalis P, Feige B, Schulze-Bonhage A, van Elst LT. Psychiatric comorbidity in patients with pharmacoresistant focal epilepsy and psychiatric outcome after epilepsy surgery. Epilepsy Behav. 2012 Mar;23(3):272-9.
- Voigt-Radloff S, Leonhart R, Schützwohl M, Jurjanz L, Reuster T, Gerner A, Marschner K, van Nes F, Graff M, Vernooij-Dassen M, Rikkert MO, Holthoff V, Hüll M. Interview for Deterioration in Daily Living Activities in Dementia: construct and concurrent validity in patients with mild to moderate dementia. Int Psychogeriatr. 2012 Mar;24(3):382-90.
- Voigt-Radloff S, Leonhart R, Schützwohl M, Jurjanz L, Reuster T, Gerner A, Marschner K, van Nes F, Graff M, Vernooij-Dassen M, Rikkert MO, Holthoff V, Hüll M. Dementia quality of life instrument--construct and concurrent validity in patients with mild to moder-ate dementia. Eur J Neurol. 2012 Mar;19(3):376-84.
Frings L, Klöppel S, Teipel S, Peters O, Frölich L, Pantel J, Schröder J, Gertz HJ, Arlt S, Heuser I, Kornhuber J, Wiltfang J, Maier W, Jessen F, Hampel H, Hüll M. Left anterior temporal lobe sustains naming in Alzheimer's dementia and mild cognitive impairment. Curr Alzheimer Res. 2011 Dec;8(8):893-901.
Hellwig S, Hüll M, Meyer PT. Negative amyloid PET imaging in a patient with probable Alzheimer's disease. Clin Nucl Med. 2011 Dec;36(12):1120-1.
Abdulkadir A, Mortamet B, Vemuri P, Jack CR Jr, Krueger G, Klöppel S; Alzheimer's Disease Neuroimaging Initiative. Effects of hardware heterogeneity on the performance of SVM Alzheimer's disease classifier. Neuroimage. 2011 Oct 1;58(3):785-92.
Voigt-Radloff S, Leonhart R, Rikkert MO, Kessels R, Hüll M. Study protocol of the multi-site randomised controlled REDALI-DEM trial--the effects of structured relearning meth-ods on daily living task performance of persons with dementia. BMC Geriatr. 2011 Aug 18;11:44.
Voigt-Radloff S, Graff M, Leonhart R, Schornstein K, Jessen F, Bohlken J, Metz B, Fellgiebel A, Dodel R, Eschweiler G, Vernooij-Dassen M, Olde Rikkert M, Hüll M. A mul-ticentre RCT on community occupational therapy in Alzheimer's disease: 10 sessions are not better than one consultation. BMJ Open. 2011 Aug 9;1(1):e000096.
Voigt-Radloff S, Graff M, Leonhart R, Hüll M, Rikkert MO, Vernooij-Dassen M. Why did an effective Dutch complex psycho-social intervention for people with dementia not work in the German healthcare context? Lessons learnt from a process evaluation alongside a multicentre RCT. BMJ Open. 2011 Aug 9;1(1):e000094.
Klöppel S, Abdulkadir A, Hadjidemetriou S, Issleib S, Frings L, Thanh TN, Mader I, Teipel SJ, Hüll M, Ronneberger O. A comparison of different automated methods for the detection of white matter lesions in MRI data. Neuroimage. 2011 Jul 15;57(2):416-22.
Voigt-Radloff S, Hüll M. [Daily functioning in dementia: pharmacological and non-pharmacological interventions demonstrate small effects on heterogeneous scales].Psychiatr Prax. 2011 Jul;38(5):221-31.
Meyer PT, Hellwig S, Amtage F, Rottenburger C, Sahm U, Reuland P, Weber WA, Hüll M. Dual-biomarker imaging of regional cerebral amyloid load and neuronal activity in dementia with PET and 11C-labeled Pittsburgh compound B. J Nucl Med. 2011 Mar;52(3):393-400.