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Department of Neurosurgery

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Home › Klinik für Neurochirurgie › englisch › Department of Neurosurgery › Research › Genetics of Brain Tumors › Publications

Publications

  • Aldave G, Gonzalez-Huarriz M, Rubio A, Romero JP, Ravi D, Miñana B, Cuadrado-Tejedor M, García-Osta A, Verhaak R, Xipell E, Martinez-Vélez N, de la Rocha AA, Puigdelloses M, García-Moure M, Marigil M, Gállego Pérez-Larraya J, Marín-Bejar O, Huarte M, Carro MS, Ferrarese R, Belda-Iniesta C, Ayuso A, Prat-Acín R, Pastor F, Díez-Valle R, Tejada S, Alonso MM. The aberrant splicing of BAF45d links splicing regulation and transcription in glioblastoma. Neuro Oncol. 2018 Jun 18;20(7):930-941. doi:10.1093/neuonc/noy007

  • Heiland DH, Gaebelein A, Börries M, Wörner J, Pompe N, Franco P, Heynckes S, Bartholomae M, hAilín DÓ, Carro MS, Prinz M, Weber S, Mader I, Delev D, Schnell O. Microenvironment-Derived Regulation of HIF Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme. Mol Cancer Res. 2018 Apr;16(4):655-668. doi:10.1158/1541-7786.MCR-17-0680

  • Oldrini B, Hsieh WY, Erdjument-Bromage H, Codega P, Carro MS, Curiel-García A, Campos C, Pourmaleki M, Grommes C, Vivanco I, Rohle D, Bielski CM, Taylor BS, Hollmann TJ, Rosenblum M, Tempst P, Blenis J, Squatrito M, Mellinghoff IK. EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer. Nat Commun. 2017 Dec 11;8(1):2035. doi:10.1038/s41467-017-02185-w

  • Heynckes S, Gaebelein A, Haaker G, Grauvogel J, Franco P, Mader I, Carro MS, Prinz M, Delev D, Schnell O, Heiland DH. Expression differences of programmed death ligand 1 in de-novo and recurrent glioblastoma multiforme. Oncotarget. 2017 Jun 28;8(43):74170-74177.  doi:10.18632/oncotarget.18819

  • Fedele V, Dai F, Masilamani AP, Heiland DH, Kling E, Gätjens-Sanchez AM, Ferrarese R, Platania L, Soroush D, Kim H, Nelander S, Weyerbrock A, Prinz M, Califano A, Iavarone A, Bredel M, Carro MS. Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression.Mol Cancer Res. 2017; 15(8):998-1011. doi:10.1158/1541-7786.MCR-16-0494 .

  • Heiland DH, Haaker G, Delev D, Mercas B, Masalha W, Heynckes S, Gäbelein A, Pfeifer D, Carro MS, Weyerbrock A, Prinz M, Schnell O. Comprehensive analysis of PD-L1 expression in glioblastoma multiforme. Oncotarget. 2017; 8(26):42214-42225. doi:10.18632/oncotarget.15031.

  • Masilamani AP, Ferrarese R, Kling E, Thudi NK, Kim H, Scholtens DM, Dai F, Hadler M, Unterkircher T, Platania L, Weyerbrock A, Prinz M, Gillespie GY, Harsh Iv GR, Bredel M, Carro MS. KLF6 depletion promotes NF-?B signaling in glioblastoma. Oncogene. 2017; 36(25):3562-3575. doi:10.1038/onc.2016.507

  • Heiland DH, Ferrarese R, Claus R, Dai F, Masilamani AP, Kling E, Weyerbrock A, Kling T, Nelander S, Carro MS. c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas. Oncotarget. 2017 Jan 24;8(4):6940-6954. doi:10.18632/oncotarget.14330

  • Kling T, Ferrarese R, Ó hAilín D, Johansson P, Heiland DH, Dai F, Vasilikos I, Weyerbrock A, Jörnsten R, Carro MS, Nelander S. Integrative Modeling Reveals Annexin A2-mediated Epigenetic Control of Mesenchymal Glioblastoma. EBioMedicine 2016 Oct;12:72-85.  doi:10.1016/j.ebiom.2016.08.050 .

  • Heiland DH, Mader I, Schlosser P, Pfeifer D, Carro MS, Lange T, Schwarzwald R, Vasilikos I, Urbach H, Weyerbrock A. Integrative Network-based Analysis of Magnetic Resonance Spectroscopy and Genome Wide Expression in Glioblastoma multiforme. Sci Rep. 2016 Jun 28;6:29052. doi:10.1038/srep29052

  • Ferrarese R, Harsh GR 4th, Yadav AK, Bug E, Maticzka D, Reichardt W, Dombrowski SM, Miller TE, Masilamani AP, Dai F, Kim H, Hadler M, Scholtens DM, Yu IL, Beck J, Srinivasasainagendra V, Costa F, Baxan N, Pfeifer D, von Elverfeldt D, Backofen R, Weyerbrock A, Duarte CW, He X, Prinz M, Chandler JP, Vogel H, Chakravarti A, Rich JN, Carro MS, Bredel M. Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression. J Clin Invest. 2014 Jul 1;124(7):2861-76. doi:10.1172/JCI68836. Epub 2014 May 27.

  • Setti M, Savalli N, Osti D, Richichi C, Angelini M, Brescia P, Fornasari L, Carro MS, Mazzanti M, Pelicci G: Functional Role of CLIC1 Ion Channel in Glioblastoma-Derived Stem/Progenitor Cells. JNCI J Natl Cancer Inst, 2013; 105 (21): 1644-1655. doi:10.1093/jnci/djt278.

  • Bredel M, Scholtens DM, Yadav AK, Alvarez AA, Renfrow JJ, Chandler JP, Yu IL, Carro MS, Dai F, Tagge MJ, Ferrarese R, Bredel C, Phillips HS, Lukac PJ, Robe PA, Weyerbrock A, Vogel H, Dubner S, Mobley B, He X, Scheck AC, Sikic BI, Aldape KD, Chakravarti A, Harsh GR 4th., NFKBIA deletion in glioblastomas. N Engl J Med. 2011 Feb 17;364(7):627-37. Epub 2010 Dec 22.

  • Carro MS, Lim WK, Alvarez MJ, Bollo RJ, Zhao X, Snyder EY, Sulman EP, Anne SL, Doetsch F, Colman H, Lasorella A, Aldape K, Califano A, Iavarone A., The transcriptional network for mesenchymal transformation of brain tumours. Nature. 2010 Jan 21;463(7279):318-25. Epub 2009 Dec 23.

  • Zhao X, D' Arca D, Lim WK, Brahmachary M, Carro MS, Ludwig T, Cardo CC, Guillemot F, Aldape K, Califano A, Iavarone A, Lasorella A., The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain. Dev Cell. 2009 Aug;17(2):210-21.

  • Lasorella A, Stegmüller J, Guardavaccaro D, Liu G, Carro MS, Rothschild G, de la Torre-Ubieta L, Pagano M, Bonni A, Iavarone A., Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth. Nature. 2006 Jul 27;442(7101):471-4. Epub 2006 Jun 28.
Head of Genetics of Brain Tumors group
Maria Stella Carro, PhD

Head: Dr. Maria Stella Carro
Department of Neurosurgery
(Neurocenter)
Breisacher Str. 64
D-79106 Freiburg