Prof. Dr. med. Sebastian Rauer
Oberarzt
Paraneoplastische neurologische Syndrome
Die wissenschaftliche Arbeitsgruppe von Professor Dr. Sebastian Rauer gehört zur Klinik für Neurologie und Neurophysiologie der Universitätsklinik sowie der Universität Freiburg.
Die übergeordneten Ziele unserer Forschung sind:
Identifizierung neuer Autoantigene/Autoantikörper bei Patienten mit klinisch klassischem paraneoplastischem Syndrom und (bislang) negativem AK-Nachweis (bevorzugt Cerebellitis und seronegative limbische Encephalitis)
Etablierung Target-gerichteter innovativer Immuntherapien bei Patienten mit klassischen PNS und bekanntem Autoantikörper (unter Abstimmung mit AG Präzisionsneuroimmunologie und Onkologie)
Berger B, Stich O, Labeit S, Rauer S. Screening for anti-titin antibodies in patients with various paraneoplastic neurological syndromes. J Neuroimmunol. 2016 Jun 15;295-296:18-20. doi: 10.1016/j.jneuroim.2016.04.004. Epub 2016 Apr 13. PMID: 27235344.
Stich O, Murek C, Rasiah C, Rauer S. Screening for well-characterized paraneoplastic antineuronal antibodies in multiple sclerosis. Int J Neurosci. 2011 Aug;121(8):477-9. doi: 10.3109/00207454.2011.580865. Epub 2011 Jun 10. PMID: 21663382.
Stich O, Jarius S, Rasiah C, Voltz R, Rauer S. Recombinant immunoblot for assessment of intrathecally synthesised paraneoplastic antineuronal antibodies in cerebrospinal fluid from patients with paraneoplastic neurological syndromes. Clin Chem Lab Med. 2008;46(12):1793-5. doi: 10.1515/CCLM.2008.354. PMID: 19055459.
Rauer S, Andreou I. Tumor progression and serum anti-HuD antibody concentration in patients with paraneoplastic neurological syndromes. Eur Neurol. 2002;47(4):189-95. doi: 10.1159/000057897. PMID: 12037430.
Rauer S, Kaiser R. Demonstration of anti-HuD specific oligoclonal bands in the cerebrospinal fluid from patients with paraneoplastic neurological syndromes. Qualitative evidence of anti-HuD specific IgG-synthesis in the central nervous system. J Neuroimmunol. 2000 Nov 1;111(1-2):241-4. doi: 10.1016/s0165-5728(00)00391-x. PMID: 11063845.
Die vollständige Literaturliste finden Sie bei Pubmed
Mitglieder
Derzeit keine
Universitätsklinikum Freiburg
- Onkologie: Prof. Dr. R. Marx, Prof. Dr. R. Zeiser
Paraneoplastic neurological syndromes research group
Professor Dr. Sebastian Rauer's research group is part of the Department of Neurology and Neurophysiology at the University Hospital and the University of Freiburg. The overarching goals of our research are:
- Identification of new autoantigens/autoantibodies in patients with clinically classic paraneoplastic syndrome and (so far) negative AK detection (preferably cerebellitis and seronegative limbic encephalitis)
- Establishment of target-oriented innovative immunotherapies in patients with classical PNS and known autoantibodies (in coordination with the Precision Neuroimmunology and Oncology Working Group)
Selected publications
Berger B, Stich O, Labeit S, Rauer S. Screening for anti-titin antibodies in patients with various paraneoplastic neurological syndromes. J Neuroimmunol. 2016 Jun 15;295-296:18-20. doi: 10.1016/j.jneuroim.2016.04.004. Epub 2016 Apr 13. PMID: 27235344.
Stich O, Murek C, Rasiah C, Rauer S. Screening for well-characterized paraneoplastic antineuronal antibodies in multiple sclerosis. Int J Neurosci. 2011 Aug;121(8):477-9. doi: 10.3109/00207454.2011.580865. Epub 2011 Jun 10. PMID: 21663382.
Stich O, Jarius S, Rasiah C, Voltz R, Rauer S. Recombinant immunoblot for assessment of intrathecally synthesised paraneoplastic antineuronal antibodies in cerebrospinal fluid from patients with paraneoplastic neurological syndromes. Clin Chem Lab Med. 2008;46(12):1793-5. doi: 10.1515/CCLM.2008.354. PMID: 19055459.
Rauer S, Andreou I. Tumor progression and serum anti-HuD antibody concentration in patients with paraneoplastic neurological syndromes. Eur Neurol. 2002;47(4):189-95. doi: 10.1159/000057897. PMID: 12037430.
Rauer S, Kaiser R. Demonstration of anti-HuD specific oligoclonal bands in the cerebrospinal fluid from patients with paraneoplastic neurological syndromes. Qualitative evidence of anti-HuD specific IgG-synthesis in the central nervous system. J Neuroimmunol. 2000 Nov 1;111(1-2):241-4. doi: 10.1016/s0165-5728(00)00391-x. PMID: 11063845.
The complete publication list can be found on PubMed.
Members:
currently none
Collaborations
University Hospital Freiburg
- Oncology: Prof. Dr. R. Marx, Prof. Dr. R. Zeiser, PD Dr. F. Scherer