Publications
from members of the Lab of Stereotaxy and Interventional Neuroscience
2023
Miguel Telega, Lidia; Ashouri, Danesh; Stieglitz, Thomas; Coenen, Volker Arnd; Döbrössy, Máté Daniel
Photometric characterization of dopamine nucleus accumbens and calcium ventro tegmental area dynamics with behavioral outcomes - Impact of different medial forebrain bundle Deep Brain Stimulation parameters. In: Brain stimulation, 16, 1, 264. 2023. https://doi.org/10.1016/j.brs.2023.01.439
Coenen, Volker Arnd; Watakabe, Akiy; Skibbe, Henrik; Yamamori, Tetsuo; Döbrössy, Máté; Sajonz, Bastian; Reinacher, Peter; Reisert, Marco
Tomographic tract tracing and data driven approaches to unravel complex 3D fiber anatomy of DBS relevant prefrontal projections to the diencephalic-mesencephalic junction in the marmoset. In: Brain stimulation, 16 (2023), 2, 670-681.https://doi.org/10.1016/j.brs.2023.03.012
2022
Bühning, Florian; Miguel Telega, Lidia; Tong, Yixin et al.
Electrophysiological and molecular effects of bilateral deep brain stimulation of the medial forebrain bundle in a rodent model of depression. In: Experimental neurology, 355, 114122. 2022. https://doi.org/10.1016/j.expneurol.2022.114122
Coenen, Volker A.; Döbrössy, Máté; Teo, Shi Jia ; Wessolleck, Johanna ; Sajonz, Bastian et al.
Diverging prefrontal cortex fiber connection routes to the subthalamic nucleus and the mesencephalic ventral tegmentum investigated with long range (normative) and short range (ex-vivo high resolution) 7T DTI. In: Brain structure and function, 227, 23–47. 2022. https://doi.org/10.1007/s00429-021-02373-x
Gardner, Wilf; Fuchs, Fanny; Durieux, Laura et al.
Slow wave sleep deficits in the flinders sensitive line rodent model of depression: effects of medial forebrain bundle deep-brain stimulation. In: Neuroscience, 498, 31-49. 2022. https://doi.org/10.1016/j.neuroscience.2022.06.023
Miguel Telega, Lidia; Ashouri, Danesh; Stieglitz, Thomas et al.
New insights into in vivo dopamine physiology and neurostimulation: A fiber photometry study highlighting the impact of medial forebrain bundle deep brain stimulation on the nucleus accumbens. In: Brain sciences, 12, 8, 1105. 2022. https://doi.org/10.3390/brainsci12081105
Tong, Yixin; Pfeiffer, Lisa-Marie; Serchov, Tsvetan et al.
Optogenetic stimulation of ventral tegmental area dopaminergic neurons in a female rodent model of depression: the effect of different stimulation patterns. In: Journal of neuroscience research, 100, 3, 897-911. 2022. https://doi.org/10.1002/jnr.25014
Coenen, Volker; Schlaepfer, Thomas E.; Sajonz, Bastian; Reinacher, Peter C.; Döbrössy, Máté et al.
“The heart asks pleasure first” - conceptualizing psychiatric diseases as MAINTENANCE network dysfunctions through insights from slMFB DBS in depression and obsessive–compulsive disorder. In: Brain sciences, 12 (2022) , 4 , 438 . https://doi.org/10.3390/brainsci12040438
2021
Döbrössy, Máté D.; Ramanathan, Chockalingam; Ashouri Vajari, Danesh et al.
Neuromodulation in psychiatric disorders: experimental and clinical evidence for reward and motivation network deep brain stimulation: focus on the medial forebrain bundle. In: European journal of neuroscience: EJN, 53, 1, 89-113. 2021. https://doi.org/10.1111/ejn.14975
2020
Ashouri Vajari, Danesh; Ramanathan, Chockalingam; Tong, Yixin et al.
Medial forebrain bundle DBS differentially modulates dopamine release in the nucleus accumbens in a rodent model of depression. In: Experimental neurology, 327, 113224. 2020. https://doi.org/10.1016/j.expneurol.2020.113224
Döbrössy, Máté; Ramanathan, Chockalingam; Ashouri, Danesh et al.
Neuromodulation in Psychiatric disorders: experimental and clinical evidence for reward and motivation network deep brain stimulation: focus on the medial forebrain bundle. In: European journal of neuroscience, 53, 1, 89-113. 2020. https://doi.org/10.1111/ejn.14975
Serchov, Tsvetan; Schwarz, Inna; Theiss, Alice, Döbrössy, Máté, Calker van, Dietrich et al.
Enhanced adenosine A1 receptor and Homer1a expression in hippocampus modulates the resilience to stress-induced depression-like behavior. In: Neuropharmacology, 162, 107834. 2020. https://doi.org/10.1016/j.neuropharm.2019.107834
Thiele, Stephanie; Sörensen, Arnd; Weis, Jasmin et al.
Deep brain stimulation of the medial forebrain bundle in a rodent model of depression: exploring dopaminergic mechanisms with raclopride and micro-PET. In: Stereotactic and functional neurosurgery, 98, 1, 8-20. 2020. https://doi.org/10.1159/000504860
Coenen, Volker A.; Schlaepfer, Thomas E.; Sajonz, Bastian; Döbrössy, Máté; Kaller, Christoph P. et al.
Tractographic description of major subcortical projection pathways passing the anterior limb of the internal capsule. Corticopetal organization of networks relevant for psychiatric disorders. In: NeuroImage: Clinical, 25 (2020) , 102165 . https://doi.org/10.1016/j.nicl.2020.102165
2019
Holz, Amrei; Mülsch, Felix; Schwarz, Martin K. et al.
Enhanced mGlu5 signaling in excitatory neurons promotes rapid antidepressant effects via AMPA receptor activation. In: Neuron, 104, 2, 338-352.e7. 2019. https://doi.org/10.1016/j.neuron.2019.07.011
Kaindlstorfer, Christine; Stefanova, Nadia; Garcia, Joanna; Krismer, Florian; Döbrössy, Máté
L-dopa response pattern in a rat model of mild striatonigral degeneration. In: PLOS ONE, 14, 6, e0218130. 2019. https://doi.org/10.1371/journal.pone.0218130
Tomov, Nikola; Surchev, Lachezar; Wiedenmann, Clemens; Döbrössy, Máté; Nikkhah, Guido
Roscovitine, an experimental CDK5 inhibitor, causes delayed suppression of microglial, but not astroglial recruitment around intracerebral dopaminergic grafts. In: Experimental neurology, 318, 135-144. 2019. https://doi.org/10.1016/j.expneurol.2019.04.013
2018
Thiele, Stephanie; Furlanetti, Luciano L.; Pfeiffer, Lisa-Marie et al.
The effects of bilateral, continuous, and chronic Deep Brain Stimulation of the medial forebrain bundle in a rodent model of depression. In: Experimental neurology, 303, 153-161. 2018. https://doi.org/10.1016/j.expneurol.2018.02.002
Tomov, Nikola; Surchev, Lachezar; Wiedenmann, Clemens et al.
Astrogliosis has different dynamics after cell transplantation and mechanical impact in the rodent model of parkinson's disease. In: Balkan medical journal, 35, 2, 141-147. 2018. https://doi.org/10.4274/balkanmedj.2016.1911
2017
Cook, A.; Pfeiffer, Lisa-Marie; Thiele, Stephanie et al.
Olfactory discrimination and memory deficits in the Flinders Sensitive Line rodent model of depression. In: Behavioural Processes, 143, 25-29. 2017. https://doi.org/10.1016/j.beproc.2017.08.006
Winkler, Christian; Reis, Janine; Hoffmann, Nadin et al.
Anodal transcranial direct current stimulation enhances survival and integration of dopaminergic cell transplants in a rat Parkinson model. In: eNeuro, 4, 5, 1-11. 2017. https://doi.org/10.1523/eneuro.0063-17.2017
2016
Furlanetti, Luciano L.; Coenen, Volker Arnd; Döbrössy, Máté
Ventral tegmental area dopaminergic lesioninduced depressive phenotype in the rat is reversed by deep brain stimulation of the medial forebrain bundle. In: Behavioural Brain Research, 299, 132-140. 2016. https://doi.org/10.1016/j.bbr.2015.11.036
Thiele, Stephanie; Spehl, Timo; Frings, Lars et al.
Long-term characterization of the Flinders Sensitive Line rodent model of human depression: Behavioral and PET evidence of a dysfunctional entorhinal cortex. In: Behavioural Brain Research, 300, 11-24. 2016. https://doi.org/10.1016/j.bbr.2015.11.026
Egger, Karl; Janz, Philipp; Döbrössy, Máté et al.
Microstructural effects of a neuro-modulating drug evaluated by diffusion tensor imaging. In: NeuroImage, 127, 1-10. 2016. https://doi.org/10.1016/j.neuroimage.2015.10.091
2015
Döbrössy, Máté; Furlanetti, Luciano L.; Coenen, Volker Arnd
Electrical stimulation of the medial forebrain bundle in pre-clinical studies of psychiatric disorders. In: Neuroscience & Biobehavioral Reviews, 49, 32-42. 2015. https://doi.org/10.1016/j.neubiorev.2014.11.018
Furlanetti, Luciano L.; Coenen, Volker Arnd; Aranda, Iñigo Alonso et al.
Chronic deep brain stimulation of the medial forebrain bundle reverses depressive-like behavior in a hemiparkinsonian rodent model. In: Experimental Brain Research, 233, 11, 3073-3085. 2015. https://doi.org/10.1007/s00221-015-4375-9
Furlanetti, Luciano L.; Cordeiro, Joacir Graciolli; Cordeiro, Karina Kohn et al.
Continuous High-Frequency Stimulation of the Subthalamic Nucleus Improves Cell Survival and Functional Recovery Following Dopaminergic Cell Transplantation in Rodents. In: Neurorehabilitation and Neural Repair, 29, 10, 1001-1012. 2015. https://doi.org/10.1177/1545968315581419
Furlanetti, Luciano L.; Döbrössy, Máté; Aranda, Iñigo Alonso et al.
Feasibility and safety of continuous and chronic bilateral deep brain stimulation of the medial forebrain bundle in the naïve Sprague-Dawley rat. In: Behavioural neurology, 2015, 1-13. 2015.https://doi.org/10.1155/2015/256196
2014
Büchele, Fabian; Döbrössy, Máté; Hackl, Christina et al.
Two-step grafting significantly enhances the survival of foetal dopaminergic transplants and induces graft-derived vascularisation in a 6-OHDA model of Parkinson's disease. In: Neurobiology of Disease, 68, 112-125. 2014. https://doi.org/10.1016/j.nbd.2014.04.009
Contreras Lopez, William Omar; Nikkhah, Guido; Maciaczyk, Jaroslaw
Embryonic stem cells in neurology – current clinical transplantation trials in Parkinson’s (PD) and Huntington’s (HD) disease. In: Arquivos de Neuro-Psiquiatria, 72, 12, 978-979. 2014. https://doi.org/10.1590/0004-282x20140154
Contreras Lopez, William Omar; Nikkhah, Guido; Schültke, Elisabeth et al.
Stereotactic planning software for human neurotransplantation: Suitability in 22 surgical cases of Huntington's disease. In: Restor Neurol Neuros, 32, 2, 259 - 268. 2014. https://doi.org/10.3233/RNN-130340
Cordeiro, Karina Kohn; Cordeiro, Joacir Graciolli; Furlanetti, Luciano Lopes et al.
Subthalamic nucleus lesion improves cell survival and functional recovery following dopaminergic cell transplantation in parkinsonian rats. In: European Journal of Neuroscience, 39, 9, 1474-1484. 2014. https://doi.org/10.1111/ejn.12541
Panksepp, Jaak; Wright, Jason S.; Döbrössy, Máté et al.
Affective Neuroscience Strategies for Understanding and Treating Depression: From Preclinical Models to Three Novel Therapeutics. In: Clinical Psychological Science, 2, 4, 472-494. 2014. https://doi.org/10.1177/2167702614535913
Piroth, Tobias; Pauly, Marie-Christin; Schneider, Christian et al.
Transplantation of Human Fetal Tissue for Neurodegenerative Diseases: Validation of a New Protocol for Microbiological Analysis and Bacterial Decontamination. In: Cell Transplantation, 23, 8, 995-1007. 2014. https://doi.org/10.3727/096368913x666449
Pauly, Marie-Christin; Döbrössy, Máté; Nikkhah, Guido et al.
Organization of the human fetal subpallium. In: Frontiers in Neuroanatomy, 7. 2014. https://doi.org/10.3389/fnana.2013.00054
Schmidt, Mischa; Kahlert, Ulf Dietrich; Wessolleck, Johanna et al.
Characterization of a setup to test the impact of high-amplitude pressure waves on living cells. In: Scientific reports, 4, 3849. 2014. https://doi.org/10.1038/srep03849