Programme
Wednesday, 17 September 2025 | ||
16:00 – 17:00 | Registration | |
Keynote Lectures and Festive Opening | ||
Chair: tbc | ||
17:00 – 17:15 | Welcome addresses by: Peter Kohl | |
17:15 – 18:00 | Calum MacRae | Cardiac electro-mechanics: from zebrafish to human |
18:00 – 18:45 | Dawn Bowles | Ex vivo organ reconditioning before transplantation: roles of the mechanical environment |
18:45 – 19:00 | Wrap-up | |
19:00 – 21:00 | Reception | Prometheus Hall |
Thursday, 18 September 2025 | ||
08:30 – … | Registration | |
09:00 – 09:15 | Rémi Peyronnet | MEC2025, Special Issue |
Session 1: Power to the Piezo! | ||
Chair: tbc | ||
09:15 – 09:45 | Yang Guo | Functional coupling between Piezo1 and TRPM4 influences the electrical activity of HL-1 atrial myocytes |
09:45 – 10:15 | Ramona Emig | Fibroblasts at the interface of cardiac inflammation and mechanical remodelling |
10:15 – 10:45 | Ana Simon-Chica | Piezo1 in cardiac immune cells and their electrophysiological relevance for the myocardium |
10:45 – 11:15 | Charles Cox | Piezo1 and fibrosis: roles of MyoD-family inhibitor proteins |
11:15 – 11:45 | Coffee break (posters on display) | |
Session 2: Stretch and Signalling | ||
Chair: tbc | ||
11:45 – 12:15 | Andrew D McCulloch | Mechanoregulation of transcription in cardiac myocytes Stretch-activation of Ca2+ sparks: role of TRPA1 channels |
12:15 – 12:45 | Yumiko Chiba | Acute stretch-induced reactive oxygen species: roles in cardiac physiology and pathogenesis |
12:45 – 14:00 | Lunch (posters on display) | |
14:00 – 14:30 | Remi Peyronnet | Stretch-activation of Ca2+ sparks: role of TRPA1 channels |
14:30 – 15:00 | Julie Bossuyt | Mechanical afterload-induced increases in Ca2+ transient and sparks: role of CaMKII nitrosylation |
15:00 – 15:30 | 2 abstract-selected talks | |
15:30 – 16:00 | Coffee break (posters on display) | |
Session 3: Stretch and Subcellular Dynamics | ||
Chair: tbc | ||
16:00 – 16:30 | tbc | |
16:30 – 17:00 | Thomas Iskratsch | Regulation of cardiomyocyte adhesion and mechanosignalling: roles of integrins |
17:00 – 17:30 | Eva Rog-Zielinska | Mechanical modulation of nano-dynamics of the transverse/axial tubular system |
17:30 – 19:30 | Posters with refreshments, and nibbles, and more… |
Friday, 23 September 2022 | ||
Session 4: Stretch and Tissue Dynamics | ||
Chair: tbc | ||
09:15 – 09:45 | Norio Fukuda | Imaging of the beating mouse heart in vivo with sub-cellular resolution |
09:45 – 10:15 | Miriam Hurley | Imaging stretch-effects on Purkinje-myocardial junctions in the whole heart |
10:15 – 10:45 | Marie-Louise Ward | Endocardial arrhythmias induced by acute ventricular stretch: role of Purkinje fibres |
10:45 -11:15 | Coffee break (posters on display) | |
11:15 – 11:45 | Fanny Vaillant | Impact of percardium on ventricular interdependence in the working heart |
11:45 – 12:15 | Jonathan Taylor | Biomechanical coupling of heart structure, coronary flow, and electrophysiology |
12:15 – 13:45 | Lunch (posters on display) | |
Session 5: Stretch and Rhythm – Acute | ||
Chair: tbc | ||
13:45 – 14:15 | Jan Christoph | Linking electrical and mechanical activation |
14:15 – 14:45 | Alex Quinn | Linking electrical repolarisation and mechanical relaxation |
14:45 – 15:15 | Axel Loewe | Differential effects of mechano-electric feedback on whole-heart electrical activation, repolarisation, and mechanics |
15:15 – 15:45 | Coffee break (posters on display) | |
15:45 – 16:45 | 4 abstract-selected talks | |
17:00 | Meeting Photo |
Saturday, 20 September 2025 | ||
Session 6: Stretch and Rhythm – Chronic | ||
Chair: tbc | ||
09:15 – 09:45 | Matt Caporizzo | Stretch-induced arrhythmia susceptibility in diabetic obese rats: role of microtubule detyrosination |
09:45 – 10:15 | Katja Odening | Mechano-electrical interactions in transgenic short- and long-QT syndrome rabbits |
10:15 – 10:45 | Lisa Gottlieb | Localized pulmonary vein scar promotes atrial fibrillation in high left atrial pressure |
10:45 -11:15 | Coffee break (posters on display) | |
11:15 – 12:15 | 4 abstract-selected talks | |
12:15 – 13:45 | Lunch (posters on display) | |
Session 7: Cool tools | ||
Chair: tbc | ||
13:45 – 14:15 | tbc | |
14:15 – 14:45 | Kevin Kit Parker | Fibre-infused gel scaffolds guide cardiomyocyte alignment in 3D-printed ventricles |
14:45 – 15:15 | Maretoshi Hirai | Development of new molecular tension indicators |
15:15 – 15:45 | Coffee break (posters on display) | |
Closing Session | ||
Chair: tbc | ||
15:45 – 16:00 | Calum MacRae | What we’ve learned and what should we focus on next in terms of mechanisms |
16:00 – 16:15 | Dawn Bowles | What we’ve learned and what should we focus on next in terms of clinical relevance |
16:15 – 16:45 | Discussion, Participant feedback | |
18:00 – 00:00 | Meeting Dinner and Dance | |
18:00 – 18:30 | Reception | |
18:30 – 18:45 | Poster Awards | |
18:45 – 20:30 | Meeting Dinner | |
20:30 – 00:00 | Entertainment |