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Programme

Wednesday, 17 September 2025

16:00 – 17:00Registration 
Keynote Lectures and Festive Opening
Chair: tbc
17:00 – 17:15Welcome addresses by: Peter Kohl
17:15 – 18:00Calum MacRaeCardiac electro-mechanics: from zebrafish to human 
18:00 – 18:45Dawn BowlesEx vivo organ reconditioning before transplantation:  roles of the mechanical environment
18:45 – 19:00Wrap-up 
19:00 – 21:00ReceptionPrometheus Hall

Thursday, 18 September 2025

08:30 – …  Registration 
09:00 – 09:15Rémi PeyronnetMEC2025, Special Issue
Session 1: Power to the Piezo!
Chair: tbc
09:15 – 09:45Yang GuoFunctional coupling between Piezo1 and TRPM4 influences the electrical activity of HL-1 atrial myocytes
09:45 – 10:15Ramona EmigFibroblasts at the interface of cardiac inflammation and mechanical remodelling
10:15 – 10:45Ana Simon-ChicaPiezo1 in cardiac immune cells and their electrophysiological relevance for the myocardium
10:45 – 11:15Charles CoxPiezo1 and fibrosis: roles of MyoD-family inhibitor proteins
11:15 – 11:45Coffee break (posters on display)
Session 2: Stretch and Signalling
Chair: tbc
11:45 – 12:15Andrew D McCulloch Mechanoregulation of transcription in cardiac myocytes Stretch-activation of Ca2+ sparks: role of TRPA1 channels 
12:15 – 12:45Yumiko ChibaAcute stretch-induced reactive oxygen species: roles in cardiac physiology and pathogenesis 
12:45 – 14:00Lunch (posters on display)
14:00 – 14:30Remi PeyronnetStretch-activation of Ca2+ sparks: role of TRPA1 channels
14:30 – 15:00Julie BossuytMechanical afterload-induced increases in Ca2+ transient and sparks: role of CaMKII nitrosylation
15:00 – 15:30 2 abstract-selected talks
15:30 – 16:00Coffee break (posters on display)
Session 3: Stretch and Subcellular Dynamics
Chair: tbc
16:00 – 16:30tbc 
16:30 – 17:00Thomas IskratschRegulation of cardiomyocyte adhesion and mechanosignalling: roles of integrins  
17:00 – 17:30Eva Rog-ZielinskaMechanical modulation of nano-dynamics of the transverse/axial tubular system
17:30 – 19:30Posters with refreshments, and nibbles, and more…

Friday, 23 September 2022

Session 4: Stretch and Tissue Dynamics  
Chair: tbc
09:15 – 09:45Norio FukudaImaging of the beating mouse heart in vivo with sub-cellular resolution 
09:45 – 10:15Miriam HurleyImaging stretch-effects on Purkinje-myocardial junctions in the whole heart 
10:15 – 10:45Marie-Louise WardEndocardial arrhythmias induced by acute ventricular stretch: role of Purkinje fibres
10:45 -11:15Coffee break (posters on display) 
11:15 – 11:45Fanny VaillantImpact of percardium on ventricular interdependence in the working heart
11:45 – 12:15Jonathan TaylorBiomechanical coupling of heart structure, coronary flow, and electrophysiology
12:15 – 13:45Lunch (posters on display)
Session 5: Stretch and Rhythm – Acute
Chair: tbc
13:45 – 14:15Jan ChristophLinking electrical and mechanical activation
14:15 – 14:45Alex QuinnLinking electrical repolarisation and mechanical relaxation 
14:45 – 15:15Axel LoeweDifferential effects of mechano-electric feedback on whole-heart electrical activation, repolarisation, and mechanics
15:15 – 15:45Coffee break (posters on display)
15:45 – 16:45 4 abstract-selected talks
17:00Meeting Photo

Saturday, 20 September 2025

Session 6: Stretch and Rhythm – Chronic
Chair: tbc
09:15 – 09:45Matt CaporizzoStretch-induced arrhythmia susceptibility in diabetic obese rats: role of microtubule detyrosination
09:45 – 10:15Katja OdeningMechano-electrical interactions in transgenic short- and long-QT syndrome rabbits
10:15 – 10:45Lisa GottliebLocalized pulmonary vein scar promotes atrial fibrillation in high left atrial pressure
10:45 -11:15Coffee break (posters on display) 
11:15 – 12:15 4 abstract-selected talks
12:15 – 13:45Lunch (posters on display) 
Session 7: Cool tools
Chair: tbc
13:45 – 14:15tbc 
14:15 – 14:45Kevin Kit ParkerFibre-infused gel scaffolds guide cardiomyocyte alignment in 3D-printed ventricles
14:45 – 15:15Maretoshi HiraiDevelopment of new molecular tension indicators
15:15 – 15:45Coffee break (posters on display) 
Closing Session
Chair: tbc
15:45 – 16:00Calum MacRaeWhat we’ve learned and what should we focus on next in terms of mechanisms
16:00 – 16:15Dawn BowlesWhat we’ve learned and what should we focus on next in terms of clinical relevance
16:15 – 16:45Discussion, Participant feedback
18:00 – 00:00Meeting Dinner and Dance 
18:00 – 18:30Reception 
18:30 – 18:45Poster Awards 
18:45 – 20:30Meeting Dinner 
20:30 – 00:00Entertainment