Dr. med. Mohamed Tarek Badr
| Telefon Büro | +49 761 270-83685 |
|---|---|
| Fax | +49 761 203-6562 |
| mohamed.tarek.badr@uniklinik-freiburg.de |
Pathogen-microbiome interaction in human response and disease-outcome during infection and colonization with Helicobacter pylori (PREDICT-HP)
Details on the study procedure:
For the study, an informative talk is held with subsequent blood sampling at the Institute for Medical Microbiology and Hygiene, and a stool sample must also be provided. For this purpose, all utensils are provided in a kit so that the sample collection can be arranged flexibly. The stool samples must be submitted to the Institute for Medical Microbiology and Hygiene. Beyond that, there are no follow-up appointments.
Are you interested?
We are seeking individuals between the ages of 18-65 years to study the pathogen-microbiome interaction associated with the human immune response during colonization with Helicobacter pylori. H. pylori is a bacterium that colonizes the gastric mucosa of about half of all people worldwide. In Western Europe, this percentage has decreased to about 20-30% in recent decades. In most cases, this colonization is harmless and may even be associated with certain benefits. However, only a very small proportion of colonized people develop diseases beyond this: Gastritis, gastric ulcers, and gastric cancer are associated with H. pylori colonization. It is still not understood why colonization is so different in different people. Using "multi-omics" machine learning approaches, we aim to address this question here.
Which requirements must be met?
- Age: 18 to 65 years old
- No pregnancy
- No diabetes
- No acute or chronic disease/complaints of the digestive tract
- No diseases of the blood coagulation system
- No antibiotics ≤ 4 weeks before the start of the study
- No severe diarrhea ≤ 4 weeks before the start of the study
Contact:
Would you like to participate in the study or receive further information? Then please contact us:
E-Mail:
anne.sophie.lichtenegger@uniklinik-freiburg.de
mohamed.tarek.badr@uniklinik-freiburg.de
Tel.: 0761 203-6585
CV
| 09/2007-02/2015 | Mansoura University Medical School |
| 03/2014-02/2015 | Practical Year in the General Hospital of Mansoura |
| 03/2015-04/2015 | General Practitioner in the Ministry of Health and Population, Daqahliyya Ägypten |
| 08/2015-02/2018 | Institute for Experimental Dermatology of the University , Lübeck |
| 03/2018 | Doctoral Degree "Identyfying mitochondrial functions modulators in Alzheimer´s disease" Institute for experimental dermatology of the University , Lübeck |
| Seit 02/2018 | Resident Doctor/ Scientist, Institute for Microbiology and Hygiene, University of Freiburg |
Clinical metagenomics Application of high-throughput techniques in clinical microbiology and recent advances in next generation sequencing (NGS) techniques have enabled us to explore a wide variety of pathogens in a broader and more efficient manner, and illustrated the complexity of the microbial communities that inhabit the human body. We are interested in harnessing these advances and implementing high-throughput techniques in infection diagnosis and treatment and study the role of the human microbiome in disease pathogenesis. |
Analysis of high-throughut data: We use high-throughput sequencing technologies in infection models to study several host-pathogen interactions. By using genomic, transcriptomic and proteomic analyses we hope to understand the role of the apoptosis system in infection-induced tumorigenesis and host microbiome modulation |
| Mitochondrial dynamics and functions in host-pathogen interactions |
Helicobacter pylori infections |
Center for Microbiology and Hygiene
Institute for Microbiology and Hygiene
Hermann-Herder-Str. 11
D-79104 Freiburg
E-Mail: georg.haecker@uniklinik-freiburg.de