Publications
Selected papers by our research groupSchlaepfer, Thomas E.; Meyer-Lindenberg, Andreas; Synofzyk, Matthis; Visser-Vandewalle, Veerle; Voges, Jürgen; Coenen, Volker A. (2021). Invasive Hirnstimulation zur Behandlung von psychiatrischen Erkrankungen. In Deutsches Aerzteblatt.
Ziesen, N. K., Killian, H. M., Schlaepfer T. E. (2020). Beyond antidepressant effects of deep brain stimulation – A systematic qualitative approach. Personalized Medicine in Psychiatry
Döbrössy, M. D. et al. (2020). Neuromodulation in Psychiatric disorders: Experimental and Clinical evidence of reward and motivation network Deep Brain Stimulation - Focus on the medial forebrain bundle. European Journal of Neuroscience.
Kilian, H. M. et al. (2020). Deep Brain Stimulation for Major Depression and Obsessive-Compulsive Disorder - Discontinuation of Ongoing Stimulation. In Psych.
Schlaepfer, T. E., & Bewernick, B. H. (2020). Deep brain stimulation for major depression: A prototype of a personalized treatment in psychiatry. In Personalized Psychiatry (pp. 83-89). Academic Press.
Coenen VA, Bewernick BH, Kayser S, Kilian H, Boström J, Greschus S..., Schlaepfer TE. Superolateral medial forebrain bundle deep brain stimulation in major depression: a gateway trial. (2019). Neuropsychopharmacology.
Coenen VA, Schlaepfer TE. Tiefe Hirnstimulation zur Behandlung der Depression (2019). Forum Sanitas, 1/2019: 39-41.
Kilian HM, Meyer DM, Bewernick BH, Spanier S, Coenen VA, Schlaepfer TE. Discontinuation of Superolateral Medial Forebrain Bundle Deep Brain Stimulation for Treatment-Resistant Depression Leads to Critical Relapse. Biol Psychiatry. 2018 Sep 22. pii: S0006-3223(18)31748-7. doi: 10.1016/j.biopsych.2018.07.025.
Bewernick, BH, Kilian, HM, Schmidt, K, Reinfeldt, RE, Kayser, S, Coenen, VA, Markett, S & Schläpfer, TE. (2018). Deep brain stimulation of the supero-lateral branch of the medial forebrain bundle does not lead to changes in personality in patients suffering from severe depression. Psychological medicine 2(4): 472-494.
Bewernick, B.H., Kayser, S., Gippert, S.M., Coenen, V.A. & Schläpfer, T.E. (2017). Acute antidepressant effects of deep brain stimulation - Review and data from slMFB-stimulation. Personalized medicine in psychiatry 3: 1-7.
Bewernick, B.H., Kayser, S., Gippert, S.M., Switala, C., Coenen, V.A. & Schläpfer, T.E. (2017). Deep brain stimulation to the medial forebrain bundle for depression - long-term outcomes and a novel data analysis strategy. Brain Stimulation 10: 664-671.
Coenen, V.A., Schläpfer, T.E., Goll, P., Reinacher, P.C., Voderholzer, U., Tebartz van Elst, L., Urbach, H. & Freyer, T. (2017). The medial forebrain bundle as a target for deep brain stimulation for obsessive compulsive disorder. CNS Spectrums 22:282-289.
Schlaepfer T, Bewernick B, Kayser S, Gippert, S, Switala C, Coenen V (2016). Deep Brain Stimulation to the Medial Forebrain Bundle in Treatment-Resistant Depression - A Placebo Controlled Clinical Study. NEUROPSYCHOPHARMACOLOGY 41, S490-S490
Allert N, Gippert SM, Sajonz BE, Nelles C, Bewernick B, Schlaepfer TE, Coenen VA (2016). Arachnophobia alleviated by subthalamic nucleus stimulation for Parkinson's disease. J Neural Transm (Vienna). 2016 Jun;123(6):631-5. doi: 10.1007/s00702-016-1546-1. Epub 2016 May 19.
Schläpfer, T.E. (2015). Deep Brain Stimulation for Major Depression-Steps on a Long and Winding Road. Biol Psychiatry. 2015 Aug 15;78(4):218-9. doi:10.1016/j.biopsych.2015.06.020.
Panksepp J, Wright JS, Döbrössy MD, Schlaepfer TE, Coenen VA (2014). Affective Neuroscience Strategies for Understanding and Treating Depression: From Preclinical Models to Three Novel Therapeutics. Clinical Psychological Science 2(4): 472-494.
Polster JD, Kayser S, Bewernick BH, Hurlemann R, Schlaepfer TE (2014). Effects of Electroconvulsive Therapy and Magnetic Seizure Therapy on Acute Memory Retrieval. J ECT.
Schläpfer T, Kayser S (2014). Tiefe Hirnstimulation bei therapieresistenter Depression. Klinische Neurophysiologie 45(2): 113-117.
Schlaepfer TE, Bewernick BH, Kayser S, Hurlemann R, Coenen VA (2014). Deep Brain Stimulation of the Human Reward System for Major Depression-Rationale, Outcomes and Outlook. Neuropsychopharmacology 39(6): 1303-1314. Altmetric Score
Markowetz A, Blasziewicz K, Montag C, Switala C, Schlaepfer T (2014). Psycho-Informatics: Big Data Shaping Modern Psychometrics. Medical Hypotheses 82(4): 405-411. Altmetric Score
Schlaepfer TE, Bewernick BH, Kayser S, Madler B, Coenen VA (2013). Rapid effects of deep brain stimulation for treatment-resistant major depression. Biol Psychiatry 73(12): 1204-1212. Altmetric Score
Holtzheimer PE, 3rd, Kosel M, Schlaepfer T (2012): Brain stimulation therapies for neuropsychiatric disease. Handb Clin Neurol 106:681-95.
Schlaepfer TE, Nemeroff CB (2012):Preface.Handb Clin Neurol 106:ix-x.
Schläpfer TE, Kayser S (2012):Hirnstimulationsverfahren: Transkranielle Magnetstimulation, Magnetkrampftherapie und Tiefe Hirnstimulation. Nervenarzt 83:95-105.
Bewernick B, Kayser S, Sturm V, Schlaepfer TE (2012):Long-Term Effects of Nucleus Accumbens Deep Brain Stimulation in Treatment-Resistant Depression: Evidence for Sustained Efficacy. Neuropschopharmacology 37: 1975-1985.
Schaefer M, Sarkar R, Weich V, Effenberger S, Friebe A, Heinze L, Spengler U, Schlaepfer T, Reimer J, Buggisch P, Ockenga J, Link R, Rentrop M, Weidenbach H, Discher T, Fromm G, Lieb K, Baumert T, Heinz A, Zeuzem S, Berg T (2010): Es-Citalopram for the Prevention of Peginterferon Alfa-2a and Ribavirin Associated Depression in HCV-infected patients. Annals of Internal Medicine 157:94-103
Schlaepfer TE, Cohen MX, Frick C, Kosel M, Brodesser D, Axmacher N, et al (2008). Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology 33(2): 368-377.
Division of Interventional Biological Psychiatry
Division of Interventional Biological Psychiatry
University Hospital Freiburg
Department of Psychiatry and Psychotherapy
Hauptstraße 5
79104 Freiburg im Breisgau
Phone: 0761 - 270 69800 (secretariat)
Fax: 0761 - 270 9669800 (secretariat)
Mail: hirnstimulation@uniklinik-freiburg.de
Secretariat (contact by phone)
Monday, Tuesday, Thursday: 9:00-13:00
Wednesday: 14-18